As for that “spray on skin” stuff, first time I used it I was warned that it “smarts a little”. Experience has shown that this is on the same scale as pouring neat bleach onto a wound (Most. Painful. Ever.), and I’ll never use it unless it’s the only alternative left.

Much better are hydrocolloid wound dressings. These have a plastic backing to support some sort of gel that you apply to the wound. Leave in place for three days and peel off to reveal raw, open flesh. Apply a second dressing, and when you peel this one off, the wound has skinned over. Unlike the spray-on skin, the plastic backing of the hydrocolloid dressings is tough enough to insulate you from regular abrasions from things like your jeans wrinkling up over the wound when you sit down.

So I have got used to trusting our tap water. I have been warned in both Germany and France not to drink tap water in Hotels as it often comes from a tank and bugs may have been breeding in same tank!
AdamDZ’z warning is sound though as we cannot rely on many water sources.
I once got a case of ‘Mexican Tummy’ (Name the country of choice by using an old Volvic bottle, filling it with tap water in the morning and driving one hot day – the contents got warm and probably incubated some bug I transferred from my mouth when gulping I had the trots for days after!
So I suggest that using a water bottle without a non-return valve on our bikes may suffer the same fate – be warned…